JOHANNESBURG — Spain's potent attack couldn't score a goal in an upset loss to Switzerland on Wednesday, when Uruguay routed South Africa 3-0 to put the World Cup hosts on the verge of some unwanted history.

European champion Spain went down 1-0, ending a 12-match winning streak and recording its first ever loss to Switzerland. Chile beat Honduras in the other Group H match, its first win at the World Cup in 48 years.

Diego Forlan scored twice in a big Uruguay win which silenced the noisy vuvuzela's in the night match at Pretoria, meaning South Africa must beat France in its last Group A match or become the first host in the 80-year history of the World Cup to go out in the first round.

"It will be a disaster for us, the home country, to go out in the first round," midfielder Steven Pienaar said. "It's going to be tough now, it's going to be difficult."

Forlan first scored from a deflected 25-meter (yard) shot in the 24th minute of the night match at Pretoria and converted a penalty in the 80th to give Uruguay its first World Cup victory since a group game at the 1990 competition.

"Obviously, as a forward I like to score goals, but the important thing is to win," Forlan said. "The team is good. We also played well against France. We're very solid."

South Africa coach Carlos Alberto Parreira complained about the penalty and was unimpressed with the outcome.

"The final result leaves me very sad because it was not a true reflection of the game," he said.

At Durban, Gelson Fernandes ran through the Spanish defense and fired in a loose ball after a scramble in front of the net that left goalkeeper Iker Casillas chasing from behind.

"To be fair, I'm not used to scoring goals, so I was a bit surprised," Fernandes said. "It was a bit of luck."

It was only Spain's second loss in 50 games.

"Today wasn't our day," Spain coach Vicente del Bosque said. "We have two games ahead of us. We have to find a way to win them."

Spain dominated possession and created attack after attack, but the stifling Swiss defense managed to withstand it all.

The closest Spain went to scoring was in the 72nd minute when Xabi Alonso hit the cross bar.

Jean Beausejour tapped in the lone goal in Nelspruit in the 34th minute to give Chile a World Cup win for the first time since June 16, 1962, when it hosted the tournament and beat Yugoslavia 1-0 for third place.

"We're very happy, and we have to enjoy this triumph," Chile forward Alexis Sanchez said. "But we have to move ahead and win the game against our next rival."

Honduras found it difficult to break through the well-organized Chilean defense.

"It's a fair result," Honduras defender Sergio Mendoza said. "We didn't have a clear chance at goal. We knew we could lose this match, but qualifying out of the group is not impossible."

South Africa had trouble containing the Forlan-led attack from Uruguay, a two-time World Cup champion, and got deeper into trouble when goalkeeper Itumeleng Khune was sent off by referee Massimo Busacca for giving away the penalty when he tripped Suarez in the area in the 79th.

"The players are annoyed, very disappointed. Everyone said it was the worst referee so far. He was giving yellow cards that weren't yellow cards." Parreira said. "He doesn't deserve to be here."

The problems extended off the field for the host nation.

Before the Spain-Switzerland match in Durban, stewards joined community activists in a peaceful protest of about 800 people outside City Hall to protest the World Cup, which they say has directed public funds away from providing housing and jobs.

Protesters held placards that said "Apartheid Still Exists" and "World Cup for All! People Before Profit."

Stewards at five of the 10 World Cup venues have been replaced by police because of a wage dispute, and FIFA and the local organizers went on the defensive about security issues.

"We have nothing further to say about the security issue, please call the police," local World Cup organizing committee spokesman Rich Mkhondo said. "They are able to answer all security-related matters. All. Not me."

Also, two Dutch women were released on bail after facing charges that they broke a law covering ambush marketing by wearing minidresses promoting a brewery at a World Cup match.

The women are being prosecuted under laws which prevents companies benefiting from an event without paying for advertising.

South African police also raided the premises of a known group of Argentine hooligans and said they will detain 17 of them.

Police had been monitoring the "barras bravas" group and observed some of them trying to get into two World Cup matches without tickets.

"They have also behaved in a disorderly fashion on a number of occasions, roughing other fans up and generally causing trouble," police said.